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Explore independent, peer-reviewed publications and scientific reviews related to peptide science and selected areas of laboratory research. Links open the original PubMed record so you can review the source directly.

Peptide Science

Recent Advances, Strategies, and Future Perspectives of Peptide-Based Drugs in Clinical Applications

Journal of Traditional Chinese Medical Sciences · 2025

A current broad review of peptide drug discovery, including stability, specificity, pharmacokinetics, delivery challenges, and emerging development strategies.

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Peptide Science

Trends in Peptide Drug Discovery

Nature Reviews Drug Discovery · 2021

A high-level perspective on how peptide therapeutics evolved, why peptides can reach difficult biological targets, and the chemistry and discovery strategies shaping the field.

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Peptide Science

Characterization of Synthetic Peptide Therapeutics Using LC-MS

Journal of Pharmaceutical and Biomedical Analysis · 2021

Explains how liquid chromatography–mass spectrometry is used to identify peptide impurities and support manufacturing and quality-control strategies.

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Peptide Science

Reference Standards to Support Quality of Synthetic Peptide Therapeutics

Pharmaceutical Research · 2023

A practical look at peptide identity, purity, strength, reference standards, lyophilization, stability, and analytical methods including HPLC, MS and NMR.

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Peptide Science

Characterization of Synthetic Peptides by Mass Spectrometry

Methods in Molecular Biology · 2024

A focused overview of mass-spectrometry methods used to verify the identity and integrity of synthetic peptides.

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Mitochondrial Research

Mitochondria-Derived Peptide MOTS-c: Effects and Mechanisms Related to Stress, Metabolism and Aging

Journal of Translational Medicine · 2023

Reviews MOTS-c signaling, AMPK-related pathways, cellular stress adaptation, energy metabolism, inflammation and aging-related research.

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Mitochondrial Research

Mitochondrial-Derived Peptides and Exercise

Biochimica et Biophysica Acta · 2021

Reviews human and preclinical evidence connecting exercise with mitochondrial-derived peptides such as MOTS-c, while clearly discussing gaps and conflicting findings.

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Mitochondrial Research

Elamipretide (SS-31): Structure, Mechanism of Action, and Therapeutic Potential

Review · 2025

A detailed review of SS-31/elamipretide, cardiolipin binding, mitochondrial structure, oxidative stress, bioenergetics, and the clinical research landscape.

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Metabolic Research

Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial

New England Journal of Medicine · 2023

The randomized phase 2 clinical trial of retatrutide, a single investigational molecule targeting GIP, GLP-1 and glucagon receptors, including efficacy and adverse-event findings.

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Metabolic Research

Effect of Tesamorelin on Visceral Fat and Liver Fat

JAMA · 2014

A randomized clinical trial examining tesamorelin and changes in visceral adipose tissue, liver fat and glucose measures in adults with HIV-associated abdominal fat accumulation.

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Metabolic Research

Effects of Tesamorelin in HIV-Infected Patients with Abdominal Fat Accumulation

Journal of Clinical Endocrinology & Metabolism · 2010

A randomized placebo-controlled trial with extension data examining visceral adipose tissue, body composition, IGF-1 and safety measures.

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Cellular & Tissue Research

Advances in the Basic and Clinical Applications of Thymosin β4

Expert Opinion on Biological Therapy · 2015

Reviews thymosin β4 biology and research involving cell migration, repair cascades, regeneration and clinical investigation.

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Cellular & Tissue Research

The Regenerative Peptide Thymosin β4 and Dermal Healing

Annals of the New York Academy of Sciences · 2012

Summarizes preclinical wound models and early phase 2 clinical research involving thymosin β4 and dermal repair.

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Skin & Matrix Research

Topically Applied GHK as an Anti-Wrinkle Peptide: Advantages, Problems and Prospective

Review · 2024

A useful critical review of GHK and GHK-Cu, including cellular findings, skin permeability, formulation questions and the limitations of available clinical evidence.

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Emerging Research

Safety of Intravenous Infusion of BPC-157 in Humans: A Pilot Study

Alternative Therapies in Health and Medicine · 2025

A very small two-participant pilot study. Included because human BPC-157 evidence is sparse; the tiny sample size makes its conclusions highly preliminary.

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About these references

External publications are provided for educational and informational purposes only. Inclusion does not imply that the authors, journals, publishers, PubMed, NIH, or any other third party endorses RVAmino Labs or its products. Research findings should not be interpreted as medical advice or as establishing safety or efficacy for any RVAmino Labs product.